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September 3, 2010

Frogs Skin..

The research team from the United Arab Emirates University have discovered a new antibiotic be developed from the skin of frogs. They succeeded in modifying chemicals to eliminate the harmful effects of the frog skin.

Scientists have produced 100 new types of antibiotics, including this one against super bacteria methicillin-resistant Staphylococcus aureus (MRSA), a bacterial "super" is famous because it can cause outbreaks of deadly infections.

"The skin of frogs is a potential source for these antibiotics. They (the frogs, red) have been around 300 million years ago, so have plenty of time to learn to defend themselves against diseases caused by microbes in the environment," said Dr. Michael Conlon, a biochemist at the University in Abu Dhabi. 

Dr. Conlon and colleagues, found a way to draw the structure of molecules in the skin of frogs, so that is not toxic to human cells but to be more powerful for humans to kill germs. Some other scientists found a way that allows the skin secretions of frogs, to avoid the attacks that damage the enzyme in the blood. The result is an antibiotic that persist longer in the bloodstream, and is more effective as a fighter against infection.

Scientists make liquid filtration over 6000 skin of frog species for the manufacture of antibiotics. The result is then purified and determined the chemical structure of the nearly 200 species that are potential for the discovery of antibiotic substances.

One of the potential for species of frog antibiotic material is yellow-legged frog Foothill. This frog comes from California and Oregon, but this frog species facing extinction. Fluid from the hairy skin of frogs also showed the success to combat the "Iraqibacter," a disease caused by bacteria Acinetobacter baumanni.

Research to find this antibiotic, conducted following the WHO's call to all members of the United Nations (UN) for the joint fight against drug resistant super bacteria antibiotics [read: WHO Calls for World War Super Bug Bacteria]. These findings were presented at the conference of the American Chemical Society in Boston.    

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